Posted by PsychoSage on April 6, 2004, at 0:26:58
In reply to Re: Equivalence between Provigil and Adrafinil, posted by pseudonym on April 5, 2004, at 23:33:32
> Yes, I knew that Adrafinil was a metabolite of Provigil. I believe a COOH was substituted for an NH2. I use about 600 mg Adrafinil in the morning rather than coffee and its fairly mentally stimulating, but boosting it to 750 seems a reasonable course of action.
You can break it up: 450mg morning/300mg afternoon - maybe 3pm
Even though the peak plasma concentration of adrafinil is reached in an hour, and I think it's like 3 for modafinil, the half-lives of the metabolites of adrafinil are longer.I don't like worrying about peaks and valleys personally.
I don't know when adrafinil kicks in again after it's original peak, but it's action isn't limited to a few hours after dosing. That's a definite.
I like breaking up modafinil in two doses over the day.
poster:PsychoSage
thread:332722
URL: http://www.dr-bob.org/babble/20040402/msgs/333187.html