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Re: Prozac and dreaming

Posted by Sad Panda on March 15, 2004, at 0:42:01

In reply to Re: Prozac and dreaming, posted by zeugma on March 14, 2004, at 17:35:40

> > Hi,
> >
> > I have been getting excessive dreaming from my Prozac (I think), and it is disturbing, and it wakes me up alot. Doe's anybody else have this problem? Is there anything I can do about it? How about taking all my med in the morning or at nite? Or, taking a long acting BZ before I go to bed to suppress my dreaming? Or, taking a low dose of TCA to suppress my dreaming? Or anything else?
> >
> > Thanks,
> >
> > Dave
> >
> >
>
>
> The excessive dreaming is probably a consequence of REM suppression combined with increased time in stage 1 sleep, which then 'takes over' the role of REM. A 5HT-2 antagonist would be the first thing to try to mitigate this effect, as it is probably mediated by excessive stimulation of 5HT-2 receptors.
>
> 5HT-2 antagonists: trazodone, nefazodone, Periactin, Remeron, many atypical AP's. Low dose TCA's might do the trick as well if you can tolerate the side effects.
>
>
>

Prozac is a very mild 5-HT2A blocker, hence the excess dreaming. When I was on Prozac it gave me nightmares & dreams of killing. That + daytime agitation caused be to drop Prozac ASAP. Next I tried Effexor which is heaps better but I had trouble sleeping, got the doc to give me Remeron & I've been having sweet dreams ever since. They are still vivid, but pleasant. Remeron's primary action is major H1 blockade which causes sedation & a calming affect. Remeron also blocks 5-HT2A, 5-HT2C, 5-HT3 & Alpha-2 NE receptors.

Cheers,
Panda.


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URL: http://www.dr-bob.org/babble/20040313/msgs/324471.html