Posted by linkadge on March 7, 2004, at 10:54:16
In reply to Re: Inositol / Lithium, posted by Metalblade on March 7, 2004, at 10:02:14
I had the EXACT same question.
Basically I was on lithium, and wanted to know if when I supplemented with inositol weather this would reverse the BDNF enhancing effects of the drug.
I have heard that inositol while does not directly enhance serotogenic function it resensitizes the serotonin receptors as well as acting as a second messenger to the serotonin system.
Lithium however blocks the presynaptic autoreceptor. When this receptor is activated serotogentic firing is attenuated. Thus blockade of the receptor keeps neurons firing. As well lithium facilitates uptake of tryptohpan into the brain. I found the effect of lithium much augmented when consumed with a high tryptophan meal.
Linkadge
poster:linkadge
thread:321523
URL: http://www.dr-bob.org/babble/20040304/msgs/321568.html