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Re: Bipolars on Wellbutrin?

Posted by PsychoSage on February 28, 2004, at 12:22:08

In reply to Re: Bipolars on Wellbutrin? » PsychoSage, posted by katia on February 28, 2004, at 0:50:06

> Hi,
> Actually I've heard numerous times over and over again that BP people should NOT take ADs alone. It can induce mania and rapid cycling as did me.
>
> I completely can relate to mixed states. And to the only sleeping 5 hours as a teenager. I remember I never slept or needed to until my 20s.
>
> Katia

Definitely. I just read some case report that basically said that Serotonin Discontinuation Syndrome can cause increased dopamine [means mania and psychosis among some other intense symptoms}. While I have experienced a less profound version, I just learned that when serotonin goes down, dopamine increases. At least this is one hypothesis. THe converse is also observed: when serotonin goes up, dopamine decreases. I guess that is why SSRIs make me apathetic, want to sleep more, and lazy.

Therefore, if I ever go back on a drug that is very specific and selective for serotonin, I will be very vigilant.


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