Posted by Chairman_MAO on February 23, 2004, at 11:03:30
In reply to Works in 90% of depressions??? (Selegiline + Ph.), posted by btnd on February 23, 2004, at 9:57:45
I have tried selegiline (10-15mg/day) with cacao capsules, which provided phenethylamine. I found that 6-12 capsules/day along with the selegiline provided a mood lift comparable to amphetamine. I once took 20 capsules and it felt like I was on speed, but without the adrenergic effects (phenethylamine is a dopamine releaser). Unfortunately, there is no commercial source that I'm aware of for phenethylamine, and the cacao capsules were not standardized.
L-phenylalanine also provides an antidepressant effect, but I found it to be too agitating, presumably because it's converted first into NE before dopamine, and the conversion to dopamine is rate-limited at that. Phenethylamine, by contrast, is a dopamine releaser, normally rapidly degraded by MAO-B, which selegiline inhibits. AM-PHET-AMINE means alpha-methyl-phenethylamine.
Have you ever tried eating a large quantity of high-quality dark chocolate on selegiline? Or taking a lot of cacao capsules (I used Nature's Way brand). You'll see what I'm talking about.
poster:Chairman_MAO
thread:316816
URL: http://www.dr-bob.org/babble/20040223/msgs/316826.html