Posted by Kon on February 12, 2004, at 19:42:57
In reply to Re: Klonopin for SP-Brad323, » Kon, posted by Chairman_MAO on February 11, 2004, at 22:29:44
>I'd like to read your references, and would be interested to hear what other people think.
Withdrawl following SSRI discontinuation has been reported to be worst than benzos both in the UK and other European countries. Most of the drugs that cause most withdrawl problems seem to be SSRIs:
www.socialaudit.org.uk/4390EU61.htm
www.socialaudit.org.uk/43800047.htm
Wrt the study using clonazepam that suggests continued long-term benefit for SAD following short-term therapy:
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J Nerv Ment Dis. 1996 Dec;184(12):731-8.A 2-year follow-up of social phobia. Status after a brief medication trial.
Sutherland SM, Tupler LA, Colket JT, Davidson JR.
Although social phobia is thought to be a chronic disorder, little is known about its long-term course in patients who engage in brief treatment studies. We, therefore, conducted a follow-up study of social phobics who had participated in a brief, placebo-controlled treatment trial of clonazepam. Of the original 75 subjects, 56 were assessed through telephone interview and self-report questionnaires that evaluated current social phobia symptoms. Information was also gathered about treatment received in the 2-year interval since the initial pharmacotherapy trial. The group as a whole showed maintenance of the gains acquired during initial treatment. On a number of symptom scales, subjects initially treated with clonazepam exhibited significantly less severe scores compared with placebo subjects. This study provides evidence of long-term benefit for social phobics when treated with a brief medication trial.
--------------------------------------------------I've never come across a similar study showing such long-term benefits with SSRIs. In fact, most SSRIS studies recommmend long-term treatment because of return of anxiety. Of course, others argue that these may also be symptoms of withdrawl.
poster:Kon
thread:311949
URL: http://www.dr-bob.org/babble/20040210/msgs/312590.html