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Re: Imipramine again » Squiggles

Posted by Sad Panda on January 20, 2004, at 1:29:01

In reply to Imipramine again, posted by Squiggles on January 19, 2004, at 8:35:29

> (not my case)
>
> I regret to report that after some
> months of a very optimistic trial
> with Remeron, this AD at the therapeutic
> average dose sputtered out. I have
> no idea why this happened - possibly it
> permitted a withdrawal effect of the
> imipramine, and allowed the depression
> to resurface. Possibly, the dose was not
> high enough.
>
> It was a great disappointment as Remeron
> had fewer side effects (except for great
> appetite) and was an anxiolytic and
> hypnotic at the same time (with clonazepam
> later adjuncted). Unfortunately, severe
> depression returned after about
> 2 and a half months. Imipramine had to be
> reintroduced.
>
> It was the best alternative of about 16-20
> drugs tried, including SSRIs and an MAOI.
> The condition is severe, endogenous depression.
>
>
> Conclusion:
>
> It seems that imipramine is
> a stronger antidepressant than
> Remeron. Imipramine also seems
> to produce more anxiety than Remeron
> (otherwise the anxiety is part of the
> depression condition). Anxiety can
> be handled easily in both ADs with the
> addition of clonazepam.
>
> Squiggles

What were the problems you had with SSRI's? Did you try adding Remeron to one of them? Have you tried Clomipramine? Sorry for all the questions & no answers :)

Cheers,
Panda.



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URL: http://www.dr-bob.org/babble/20040118/msgs/303061.html