Posted by Shandra on October 29, 2003, at 18:28:00
In reply to Re: Zoloft or Wellbutrin rollercoaster ride sensation? » Snoozy, posted by Katia on April 19, 2003, at 3:15:46
Dear Katia - I'm new to the site so I'm responding to a post from earlier this spring. Hope things are better for you. I wanted to mention that last spring and summer I was on Wellbutrin SR and had better results on the depression than Zoloft (which I took a couple of years ago - the Zoloft helped some but not nearly enough and I had a variety of side effects). I was taking 150mg Wellbutrin two times a day, just about exactly 12 hours apart as is recommended in the product literature (and my pdoc of course)... I had few of the normal side effects with Wellbutrin @ 300mg (for example, weight gain was not a big problem). However, I felt like 300mg a day was not taking care of my depression, even though it was "supposed to" - seems a lot of people assume that 300mg a day is a "Therapeutic Dose" even if it isn't doing the trick - ha! Well, after 'firing' this pdoc I was seeing (he was more interested in collecting a weekly fee for psychotherapy and didn't really know his stuff as far as meds went), I found a pdoc who really knew his stuff. After trying various things, including a mood stabilizer, we jointly decided to bump me up to 200mg twice a day (sustained release - I was told recently the company only makes a sustained release - could other posters be talking about a generic, possibly gotten in Canada, that is not sustained release? I got deadends when trying to find alternatives). Imagine my surprise when the 400mg of Wellbutrin per day really made an impact in my depression, but the flip side was that I was ANGRY all the time! It's like it gave me enough energy and relief from depression to not be a doormat, but it seemed to push me to the other extreme with irritation and being angry with things (and people, like bosses and significant others) whereas I normally wouldn't react that way at all. Since my pdoc & I had been very careful to add/change only one thing at a time, I am 100% certain that Wellbutrin was what was causing this aggitation & aggression.
It may seem like there should not be such a huge difference between 300mg and 400mg per day, but I found it to be an extreme difference in my moods, both for better & for worse.
Good luck!
-Shandra> Thanks Snoozy,
> Unfortunately I do not have the option to take it easy for a few days...for some crazy reason all these intensity has happened upon me at the same time. This woooooozy feeling, skipped heartbeats, Grad school is esp. intense now as well as work. I want to quit both and almost did today! My mood is out of control. I almost told my boss exactly what I thought in the midst of tears and yelling. But I bit my tongue for as long as I could and it passed...My mood was almost, and I say almost completely out of my control. But need to just hang on for a few more days....
> toooooooo many bills each month to not hang on...
>
poster:Shandra
thread:90018
URL: http://www.dr-bob.org/babble/20031025/msgs/274778.html