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Re: Attention Female Strattera users

Posted by MamaB on October 29, 2003, at 6:30:11

In reply to Re: Attention Female Strattera users » MamaB, posted by loolot on October 27, 2003, at 20:39:44

Loolot,
Sorry it has taken me a while to get back to you. here is the crux of what I have found:

1.Estrogen has some effect on the Tyrosine Hydroxolase which is the "rate controlling mechanism" (enzyme) produced in the hypothalamus that limits the production of norepinephrine.

2.Estrogen is reported to inhibit extra-neuronal uptake of norepinephrine, thus increasing norepinephrine concentrations.

3.Some very early studies (Sawyer et al. 1949-1950) with rabbits indicated that administration of drugs that block norepinephrine/epinephrine when administered at the highest point of production of the estrogens, prevents/inhibits further release of LH (lutenizing hormone) precursor to FSH and therefore to estrogen.

About the only conclusion I have drawn here is that there is a correlation of some sort. I plan to show all of this to my psychiatrist and see what he thinks.
Sorry it is not more conclusive, I will keep reading. MB


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poster:MamaB thread:274037
URL: http://www.dr-bob.org/babble/20031025/msgs/274559.html