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Re: whats the typical cytomel dosage for depressio » loolot

Posted by tealady on October 12, 2003, at 5:44:20

In reply to Re: whats the typical cytomel dosage for depressio » tealady, posted by loolot on October 11, 2003, at 13:09:21

> THANKS!! tealady you are an expert!

not really
> Are you on T3? Are you on it permanently or do you go on and off? Ar eyou hypo thyroid or is it for depression?

I'm on THYROID extract (armour (usually) in the US) plus T4..there is T3 in it. I tried adding T3 but it stimulates my appetite so much I need to sew my lips together!..so I stopped it.

>
> > It's not really resistance. The cytomel in your blood feedbacks to the pituitary and hypothalmus..and this lowers yoour TSH (thyroid stimaulting hormone)..and this means your own thyroid is stimulated less to make its own thyroid hormones. It's a part of the way all our bodies regulate themselves.>>
>
> So in that case if I just stayed on a low amount of cytomel would my thyroid be the same bc it was a little low? Or is one thyroid level always low if it is low to start, does it regulate itself to be low?
>

It's individual ..occasionally adding in a little , especially T4, can make it lower..a litle T3 is safer in that way from what I've seen
BTW if one is older or has low adrenal or is unfit with heart conditions etc..they do not tolerate even 5mcg T3 added in, so I gathered you were on the young side and fit if your doc put you straight onto 25mcgT3


> > You can keep putting more and more it until you totally turn off(or almost) your own thyroid hormone production. You thyroid gland may then start to shrink as it is no longer being used?(some docs think so)>>
>
> Can you give me some linkds to this info? Any particular docs/studies?

Nope..all only my opinion from observation, personal experiences of many,..oh the shrinking bit I got told of by an endo whose brains I picked for 30mins or so. My ultrasound shows mine is a bit shrunk..and she reckoned is was because of the thyroid hormones and TSH level I was maintaining.., as I didn't have an ultrasound prior to meds cannot prove or disprove this..but they do use thyroid hormone to try to shrink nodules and over enlarged thyroid glands sometimes successfully..it does make sense. Luckily thyroid glands , if healthy can regrow..

>
> <<> Also TSH (or perhaps thyroid hormones) and leptin have a feedback thingy too..and leptin controls appetite/ metabolism/weight etc as well..so it is currently thought by some that you should probably not lower your TSH too much (like below 0.5)..and TSH is probably also involved in many other things in body..definitely thyroid hormones are. >>

I think they are some studies out now on TSH and leptin levels if you look thru pubmed, this is an area being researched lately.

> I wonder if adding synthroid would help balance things out?
that depends. T3 is much better for depression and weightloss usually..
but I myself feel (I think) that I needed a bit of T4 to even out my hormones...T4 should be mainly a "store" for your T3..something you can call on for conversion on demand if needed.Something that can give you a steady supply of T3.
Typical "human" ratios are 10:1 (T4 to T3)
...but then you need everything functionally optimally..especially your liver, for conversion (and this may be a problem). If you do add some T4 add in some selenium to help conversion (probably 50mcg to 75mcg for females in US is enough daily).
Some folks fo best on T3 alone..some on natural thyroid ", most women apprently need at least some T3 in their meds..and guys seem to usually handle T4 only better. This is a generalisation! Everyone is individual..and that's the difficulty..you and your doc have to work it out yurself.
I felt too "up and down" with not enough T4, but sme parts of me work better with more T3...go figure!

>
> > So what happens by the time you hit around 50mcgT3 you are probably near a total replacemnt dose for your body..so your own TSH will probably be very low..and your own thyroid production has a rest...it's very individual how much this takes..one of the variables is your weight.>>
>
> So what dose do you think is safe to stay on? Under 25?

no idea .. Have you ever asked for a TSH, FT4, Ft3 test..just to see where you are? When on T3 only the TSh is often a bit suppressed..so go by Ft3 and Ft4. Some do better on slow released T3 also.

>
>
> > I went looking for some references.
>
> >
> > Please note: Wilson did go out of practise >>
>
> Why?

I don't know any more than in the links I gave you. If you are reading in the thyroid forum..click on "advanced mode" at the bottom RHS of page to get 20 at a time instead of individual postings..and start reading. That is where I gained most of my "knowledge".

Also the links to wilsons syndrome epages..you just have to read thru them all.

>
>
> > Also I only know of a couple of people who have tried Wilsons' personally and they have both had to stay on T3 meds..they couldn't get off themselves. >>
>
> Why?

"again just read in the forum from links..why..They just can't get off as they go back hypo..so they are staying on. One used to be treated by him before he stopped practising and really like him, but she is now into Chinese medicine treatments
>
> >
> > On the other hand my own doc is on T3 SR and thinks its great, she looks great too, and is going great..she is on about 45mcg I think.
> >>>
>
> Is she on permanently? Did her hypothyroidism show up on the blood test or did she just feel that way?

Yes, I guess so. Not really hypo on blood tests (myself, I was only borderline TSH and Ft3, Ft4 wewre OK'ish).
Doc was OK on blood tests too..but with her, she had a highish Ft4 and lowish Ft3 and her Rt3 was highish..so it makes sense that she would benefit from T3 alone..as that is all she needs, and it gets over her conversons problems.
And also it doesn't seem, for her, to stop her body producing the T4. Like I said, everyone is indivual.

> Is she an endo?

Nope, just a GP. Into hormones though, attends conference etc on the stuff. Very difficult to find a endo who does treat with T3 or a mix..most endos are "into" diabetes more, and are not THAT into thyroid. P-docs treat more with T3 or a mix than endos.

>
> >
> > Another would be pulse..if hypothyroid it can be slow(like in an athlete but you usually aren't fit..around 60'ish..it's low as your whole body is slowed down).>>
>
> My blood pressure has always been slightly low. Is this an indication of hypo? My body temp has always been on the low side, too, not dangerous, but on the low side
>

Mine was low before thyroid meds and adrenals were treated. I went from a usual 90/60 to a usual 120/80. I acually got my blood pressure UP to 90/60 by adding in lots of salt. Before then everything was always dizzy and I fell etc.

Overall I think blood pressure may be possibly be more a sign of low adrenal function..but I guess when I tried adding in 2000mg of tyrosine a couple of weeks ago for one day it sent my blood pressure up to 135/88? think from memory..so if it could go up with tyrosine...no, that could be the tyrosine affecting the adrenals too.
The blood presure comments were made based on what others have said. I don't have my own blood pressure monitor..but I try to get it checked as often as possible and what I said was experienced by others ..who do monitor their own blood pressure. The comments do fit my experiences though with headaches etc.

>
> Thanks so much for all of your help! This is the best info on this I have found so far, and I have been searching!
Thanks, I was hesitant to reply as it IS complicated and not really as you say no scientific documented trials etc...but then I was concerned you might go a bit hyper
Jan


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poster:tealady thread:265752
URL: http://www.dr-bob.org/babble/20031010/msgs/268617.html