Posted by DSCH on September 19, 2003, at 22:19:13
In reply to Re: Non-stimulant, Non-TCA for ADHD? « Francesco, posted by Dr. Bob on September 15, 2003, at 20:12:59
> > Thank you for your kind reply. Yeah, it seems something like ODD.
> > "having NE reuptake inhibition and then antagonizing some of the NE receptors" ... Why does Anafranil has both properties ?Beats me. :-)
> > Could you explain to me what is the half-life of the meds ? For ex. Imipramine 19 hrs, (8-20 hrs).
> > Why three numbers ?Low, medium, high numbers correspond to fast, average, and slow metabolizing of the compound by individuals
> > Does it mean that if I take Imipramine after 20 hours there won't be any trace of the med in my body ? (Clomipramine 19-37 hrs)
No... at that point serum level of the drug would be at one half maximum from a single dose.
> > mumble mumble ... does it mean that I could take Imipramine only when I need it for daily use ? Interesting issue ... since here Tofranil is considered the best TCA for ADHD ... It's less serotoniergic and more NEergic ... seems interesting : ) (I'll ask about Clonidine ... I think Guanfacine is a med of the same class)
> >
> > P.S. I red before posting your new post ... I usually stayed on it for ten-eleven months then stop it on summer than re-take it. And I did this for 5-6 years. Maybe some anxiety can taper off in the long term but the social avoidance usually lasts ... Besides the "ODD problem" I don't enjoy very much staying with people when I'm on it ... I easily get bored and want to go back home and reading my books ... Furthermore and unluckly sexual disinterest and weight gain doesn't taper off : ) (I know, it would be the same for Tofranil : /)
>Keep the slective NE-RIs in mind too.
What's been going with you lately? Update? :-)
poster:DSCH
thread:260422
URL: http://www.dr-bob.org/babble/20030917/msgs/261804.html