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Re: Parnate

Posted by JonW on September 19, 2003, at 11:10:22

In reply to Re: Parnate » cybercafe, posted by Nohope on September 19, 2003, at 3:08:01

> I am finding it difficult to reconcile your experience with what I read elsewhere. Are you able to provide evidence other than your personal experience that Parnate does not negatively impact on sexual function? (I am trying not to get my hopes up about yet *another* medication that has 'no' negative sexual side-effects...that is, until you try it...)

I can say, for me, Parnate increased libido, but it also made me impotent along with the usual anorgasmia... a most frustrating complication. Not quite as bad as Nardil for sexual side-effects, but pretty close.... impotence was actually worse....

Moclobemide didn't cause me any of these problems. But I do concede, if you're looking for a cure in a single drug, moclobemide doesn't seem to work for a lot of people. It works for jaynee and I, though! :) I am curious if people who didn't do well on this drug stayed on it long enough or at a high enough dose. The greatest effect for me wasn't felt until beyond 8 weeks. I recently read an old abstract from 1992 noting significant improvement between weeks 8 and 16 for social phobia, and my experience was the same for depression. Actually, it's more effective for my depression than SP (it definitely helps, though, comparable to the SSRIs), but I've never found *any* drug that removes my SP (That's what CBT is for!). There is plenty of information out there confirming moclobemide's lack of side-effects, particularly the sexual side-effects. Of course, it also seems to be somewhat less potent than other drugs. If you haven't tried it, I think it's worth a shot. If it doesn't work, there's no withdrawal for most people and you can start a new drug as soon as 24 hours after you stop it. Compare that with the withdrawal of the classic MAOIs and the 2 week washout period.

My symptoms are atypical depression/social anxiety disorder/ADD. All of these are very severe. I am also very irritable and agitated at times. It has been suggested by some that I may be bipolar (isn't everyone these days?) or have temporal lobe epilepsy. I've been hospitalized twice. Moclobemide + L-Theanine + CBT has been extremely effective for all of my symptoms. It takes a long time to completely undo a lifelong illness, but for the first time I feel well on my way. I'm actually glad to be me... if that makes any sense.

Good Luck,
Jon :)


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Psycho-Babble Medication | Framed

poster:JonW thread:260754
URL: http://www.dr-bob.org/babble/20030917/msgs/261613.html