Posted by CamW. on September 8, 2003, at 9:56:52
In reply to Re: lack of sleep, posted by Bill L on September 8, 2003, at 8:36:09
Bill - Almost all OTC sleep-aids contain the antihistamine, diphenhydramine (eg. Benadryl™). Sleep is induced by the strong antimuscarinic properties of this drug (a similar side effect is seen with Clozaril™ (clozapine).
The main problem with using OTC antihistamines for sleep is that although they do put you to sleep, they don't give you a restful sleep. The antihistamine prevents one from attaining REM sleep. The REM (rapid eye movement) phase of sleep is the dream phase, where the body is thought to be consoldating and strengthening certain synapses, grow new neurons/dendrites, and prune others.
If OTC sleep-aids are used on a very regular basis, one runs the risk being more tired than they would have been had they stayed up all night. In other words, these OTCs will get you to sleep, but they won't give you a restful sleep.
Just some thoughts - Cam
poster:CamW.
thread:257820
URL: http://www.dr-bob.org/babble/20030907/msgs/258036.html