Posted by Larry Hoover on August 29, 2003, at 7:58:32
In reply to FISH OIlS NOT FOR ALL, posted by freedom2001 on August 29, 2003, at 0:25:07
> Pyrrole Disorder
>
> Omega 3s can worsen mental symptoms in bipolar or schizophrenic patients.... if they have a pyrrole disorder.That's a pretty big if, in my opinion. There is a large body of evidence that both bipolar and schizophrenia are associated with defects in omega-3 metabolism, resulting in a substantial decrease in phospholipids with DHA in the sn-2 position. Rather than having a deficit of arichidonic acid, as you suggest, they have too much (relatively, as arichidonic is the usual substituent for DHA, if there's a deficiency). So, I have to wonder about the relative rarity of your defined class.
> This phenotype is dramatically short of
arachidonic acidMeat is an excellent source, and also supplies a good amount of zinc.
> & giving omega 3 oils aggravates the situation since omega 3 and omega 6 EFA's are in competition for delta 5,6 desaturases.
No competition, if given in the preformed state. Fish oil would bypass those enzymes, and permit all the dietary omega-6 virtually unhindered access. But, wait! That's exactly what is happening already, wherever the Western-style diet exists.
> We use red blood cell membrane analysis for EFA's
> if we suspect this problem.
>
> Pyroluric mental patients will usually get worse if given fish oils, DHA, EPA, etc. They thrive on Primrose Oil, a good source of AA and other omega 6s. (June 23, 2003)Primrose oil is *not* a source of arichidonic acid. It does contain omega-6 fatty acids (especially gamma-linolenic), but all vegetable oils have omega-6 fats.
Lar
P.S. I have a real problem with pseudo-science.
poster:Larry Hoover
thread:255219
URL: http://www.dr-bob.org/babble/20030828/msgs/255273.html