Posted by Larry Hoover on August 10, 2003, at 11:44:26
In reply to Re: 20mg of Klonopin??, posted by cubbybear on August 10, 2003, at 4:54:38
> I'm always pretty surprised when I read about people who suffer no adverse effects after mixing benzos with alcohol. I had always thought that that combination of CNS depressants would almost surely be fatal. What's the word on this? (maybe I'm thinking of the old barbiturate drugs and alcohol)
This happens to be one of those cases where individual variability in genetic factors is the major determinant of the outcome. There is no way to predict what will be a lethal dose, a priori. Alcohol and benzos combined can kill. What dose will kill a particular individual can only be determined by experiment, which will unfortunately, render that knowledge moot.
BTW, what proves lethal is the suppression of respiration. It's not toxicity that kills. It's the lack of oxygen.
Lar
poster:Larry Hoover
thread:249522
URL: http://www.dr-bob.org/babble/20030807/msgs/249784.html