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Re: There's also brofaromine » Ame Sans Vie

Posted by zeugma on August 9, 2003, at 17:47:01

In reply to Re: There's also brofaromine » SLS, posted by Ame Sans Vie on August 9, 2003, at 10:16:02

> Gee. Sounds like brofaromine should be contraindicated in people taking brofaromine, lol! I mean, with the combined MAO-A inhibition and 5-HT reuptake inhibition, wouldn't there be the same risk of serotonin syndrome as taking, say, Nardil with Zoloft? Perhaps that's why it's no longer sold?


According to an abstract i just looked at (from 1999), "Our findings indicate that BRO and MOC are as effective as tricyclic antidepressants, and they are better tolerated. However, BRO is not being studied at present, for reasons unrelated to efficacy or side effects."

It's no doubt related to the perception (which the authors share) that the RIMA's are less effective than the irreversible MAOI's. But if RIMA's are 'only' as effective as TCA's, doesn't that make them MORE effective than SSRI's?


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