Re: Nacin (or niacinamide) for BP II Irritabilty » Barbara Cat

Posted by Ron Hill on June 5, 2003, at 11:17:55

In reply to Re: Life without a moodstabilizer? » Ron Hill, posted by Barbara Cat on June 5, 2003, at 1:26:56

Hey Barbara,
> Are you also taking B complex? You probably know this cause you seem well versed in nutrition but all the same, just taking B3 could cause an imbalance.
Yeah, I’m aware of what you’re talking about and I take a B-100 complex daily.
> You know, B3 is used in the synthesis of dopamine as in tyrosine -> phenylalanine -> dopamine with thyroid precursor thrown in along the way, so maybe niacin is helping you to metabolize dopamine for a lift?
I was unaware of this role that B3 plays in the production of dopamine. However, I'm convinced that B3 is doing an incredible job treating my irritability by improving serotonin production (as opposed to dopamine). As I understand it (and correct me if I'm wrong), if the body does not absorb adequate amounts of B3 from the diet, the body will manufacture in own supply of B3. However, it is a costly manufacturing process in that it uses up 60 tryptophan molecules for every one B3 molecule produced. Therefore, by supplying my body with plenty of B3, a large reservoir of tryptophan can now be used for the production of additional serotonin. I believe that it is this increased production of serotonin that is erasing the irritability (flash rage, sever impatience, etc).
I love the increased motivation, drive, and focus that comes with improved dopamine pathway functioning. For example, Enada NADH increases the production of dopamine and I love it. However, if my dopamine levels get out ahead of my serotonin levels, I get irritable (GRRRRRRRRR!). This is my naive and immature pharmacological explanation which may or may not have any semblance of fact. But what I do know is when I raise serotonin levels (using SSRIs, 5-HTP, etc) the irritability subsides. And now B3 is doing this for me without the adverse side effects of the SSRIs.
-- Ron

Thread

Anyone else have THIS KIND of depression ??? Janelle 5/30/03
...
Re: Barb, Re: Anyone else have THIS KIND of depression » McPac Barbara Cat 6/2/03
Re: BarbCat, Re: Anyone else have THIS KIND of » McPac Barbara Cat 6/2/03
No reason for you to be indignant. (nm) » Larry Hoover Paulie 6/2/03
Re: No reason for you to be indignant. » Paulie Larry Hoover 6/3/03
Re: Life without a moodstabilizer? » McPac Ron Hill 6/4/03
Re: Many many thanks, Lar. It's late, more later. (nm) » Larry Hoover Ron Hill 6/4/03
Re: Thank you very much for your anecdotal info (nm) » Barbara Cat Ron Hill 6/4/03
Re: Good attitude Paulie! Thanks for your info (nm) » Paulie Ron Hill 6/4/03
Thanks for the personal account on Lithium Orotate (nm) » Barbara Cat Paulie 6/4/03
BarbCAT: answers 2 your questions: » Barbara Cat Janelle 6/4/03
Re: BarbCAT: answers 2 your questions: » Janelle Barbara Cat 6/5/03
Re: Life without a moodstabilizer? » Ron Hill Barbara Cat 6/5/03
Re: Nacin (or niacinamide) for BP II Irritabilty » Barbara Cat Ron Hill 6/5/03
Anybody? Re: Life without a moodstabilizer? McPac 6/5/03
Re: Nacin (or niacinamide) for BP II Irritabilty » Ron Hill Barbara Cat 6/5/03
Re: Anybody? Re: Life without a moodstabilizer? » McPac Barbara Cat 6/6/03
Thanks Barb! (nm)Re: Anybody? Re: Life without McPac 6/7/03
Re: Enada NADH and 5-HTP » Barbara Cat Ron Hill 6/7/03
Re: Enada NADH and 5-HTP » Ron Hill samplemethod 6/7/03
Re: Vitamin B3 » samplemethod Ron Hill 6/8/03
nieper writings on LITHIUM OROTATE glutamate joebob 8/2/03
wonder what happens to the lithium levels of joebob 8/2/03
Re: LITHIUM OROTATE destinie 8/18/03
Re: Larry what do you think about lithium orotate? » Larry Hoover tealady 9/2/03
Re: Larry what do you think about lithium orotate? » tealady BarbaraCat 9/2/03
...
Redirect: what do you think about lithium orotate? Dr. Bob 9/7/03

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