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Re: phenylalanine etc. » JackT

Posted by Larry Hoover on May 30, 2003, at 16:51:04

In reply to Re: Mg? How you making out finding it? » Larry Hoover, posted by JackT on May 30, 2003, at 11:25:15

> Lar,
>
> I haven't had a chance to go to Wal-Mart yet. I'll try there first this week-end and then the on-line store you recommended.
>
> I've got another question for you. What is your take on d-phenylalanine as a precursor to phenylethylamine? Do you suspect it would work as a mild anti-depressant?

What I like about it is it's something in your control. It's effect may be subtle, perhaps more noticeable. But you're using your body's machinery the way it was intended to be used, ya know?

L-phenylalanine can get streamed two way....towards PEA, or towards dopamine. D-phenylalanine can only go to PEA. Moreover, it suppresses diversion of L-PA from going towards PEA. So, I generally recommend DLPA, the racemic mixture of d-,l-phenylalanine. Can't hurt. Might help. Take on an empty stomach. Some time that day, make sure you get some B-complex, to make sure the old enzymes are all fired up.

> I have been looking for something that would make me feel good again. Between the GAD, social phobia, and the benzos, I just don't enjoy life. I go through the motions everyday but I'm always mildly depressed (nothing clinical). I've been considering Nardil, mainly because of Ace, selegiline (although my current pdoc won't prescribe it) and mirapax (sp?). Do you have any guidance of drugs or supplements with a lasting dopamine boost or other mood-lifting mechanisms? I'm willing to try almost anything if it looks promising. Maybe this is an impossible question to answer and I probably have asked it before. Anyway, it doesn't hurt to keep probing.
>
> Jack T.

There are lots of ideas. Ron mentioned NADH. It directly contributes to dopamine activity. Niacinamide can be soothing (anxiolytic), and also contributes to NADH downstream. Magnesium should have a calming effect, but as many people have noted, there are substantial differences in dose-response. Moreover, magnesium can potentiate (make it seem like you took a higher dose of) your benzos. Be a little cautious. Selenium has been shown to increase measures of well-being even in "normal" people, but also in depressed ones. Fish oil has a general mellowing/resiliency effect for a lot of people. Vitamin C gives some people mental clarity, and we're just getting reports of the same thing from vitamin E. Alphalipoic acid is another antioxidant with psychotropic activity.

There are many things you can try, but just take it slow. You didn't get sick in one day, so it's best to patiently try things, see how they fit in (or not). Go off something, try it again later, to see if the effect is the same. We're talking lifestyle changes here.

Lar

 

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poster:Larry Hoover thread:229017
URL: http://www.dr-bob.org/babble/20030530/msgs/230294.html