Posted by Ron Hill on May 21, 2003, at 21:42:39
In reply to Re: Niacinamide reduces irritability (anecdotal) » Ron Hill, posted by Larry Hoover on May 21, 2003, at 11:14:36
Larry,
Thanks for your post.
> Hey, Ron. I'm a little surprised to find that you had classic niacin flush from niacinamide.
Figures I'd get caught in my lie. Johnj emphasized the need to take niacinamide (as opposed to niacin), however, my wife takes niacin periodically so I tried some of what we already had laying around the house until I can get over to the nutritional store to buy some niacinamide. I lied in my post and said that I took 500mg of niacinamide (when I actually took 500 mg of niacin) so that my friend Johnj would not yell at me.
Why is niacinamide preferable to niacin, anyhow?
> Just go to Pubmed and plug in "niacinamide diabetes". Maintenance doses are 25 mg/kg, which is 1750 mg/day for your typical 70 kg adult male. In other treatment protocols, doses of 60 mg/kg are used.
Thanks, Larry; I'll check it out. <How do you know if I am lying or telling the truth?>
> Just for the record, irritability is one of the symptoms of niacin/niacinamide deficiency. Perhaps you've got a genetic biochemical quirk that requires a little "helping hand" with supplementation?
Maybe; I don't know. It does seem to reduce my irritability quite noticeably. But now I'm having trouble with my atypical depression. I'm not sure what's going on. I went two weeks between Enada NADH doses, so maybe that's it. Part of me wants to speculate that niacin (NAD) counteracts the antidepressive effects of NADH. Enada NADH reduces my atypical depression but increases my irritability. On the other hand, NAD reduces my irritability, but might it also be adversely affecting my atypical depression? Who knows. What I do know is that I've gotta suck it up and get myself out of this low motivational, apathetic pit.
Thanks again, Larry and John.
-- Ron
poster:Ron Hill
thread:223158
URL: http://www.dr-bob.org/babble/20030520/msgs/228231.html