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Re: Seratonin/NE Agonists, Is Remeron the only one?

Posted by SLS on May 19, 2003, at 16:26:08

In reply to Seratonin/NE Agonists, Is Remeron the only one?, posted by Jack Smith on May 19, 2003, at 16:06:28

> Is Remeron the only US approved antidepressant med thats principal method of action is to act as an agonist of seratonin and norepinephrine sites?

Hi Jack.

The major metabolite of Buspar (buspirone) acts the same way Remeron does at NE alpha-2 presynaptic autoreceptors. Buspar itself is a 5-HT1a partial agonist.


- Scott

 

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