Posted by lady fever on April 19, 2003, at 17:15:05
In reply to Re: Not sleeping on Celexa, posted by linkadge on April 19, 2003, at 16:59:55
One more question: are there any antidepressants that won't bind to the 5ht-2 receptors, but will bind to some of the other serotonin ones? SSRI or otherwise?
Thanks in advance.
> It's unfortunate but this is a potential side effect of all the SSRI's.
>
> The SSRI's increase serotonin availablity at all serotonin receptors in the brain. Some of those recptors are involved in sleep, but others, especially 5ht-2 are involved in alertness and anxiety regulation. Too much serotonin at these receptors and you can be anxious and have slight activation.
>
> This side effect does lessen over time and can be emproved by morning dosing. Certain meds like trazadone and remeron block these receptors resuting in better sleep. If you are still not sleeping, the adition of trazodone usually helps
>
> Linkadge
poster:lady fever
thread:220713
URL: http://www.dr-bob.org/babble/20030417/msgs/220720.html