Posted by matt66 on March 6, 2003, at 15:48:32
In reply to Re: EXP'NCED P'BABLRS PLS:dont forget Remeron , posted by stjames on March 5, 2003, at 16:50:40
> > It has been established . . . in their advertising.
> >
>
> Advertising is not clinical proof.
> There has yet, in 50 years been an AD that works
> quicker than 4 weeks for the general population.
> Many claim, not produce.
> Many on this list confuse initial effects with the true AD effect.i may be one of those who confused initial effects with the true anti-depressant effect. i was depressed for + 10 years, but so functional and able to hide it, that even my psychiatrist father didn't recommend i try ad's until I was 18 (about four years ago). we raced through a few tca's (i've ben in college and the pressure and impatience made it impossible to sit on a med). eventually i tried marplan for a week (no effect), and then nardil, and within 48 hours I was a different person completely. social anxiety/self-consciousness/self-loathing/inferiority complex/nervousness all went away. in their place- increadible levels of creativity, confidence/sucess with girls/peaceful mind/ actually noticing the effect of my positive vibes on other people rather than that feeling of awkwardness people would have around me due to the deprerssed vibe i was sending out. increased energy, focus, sense of humor- i couldn't have dreamed a med could do all that. i didn't even realize how bad i had it till i came out of the fog. but, after three weeks, i felt it slipping. i was able to recall how i felt initially and act out the role/personality i experienced on the nardil and was in a better spot than before (probably from having had so many insights on the nardil and therefore gaining a different perspective on life). however, three weeks of remission plus another couple weeks of residual effects, and i had to tell my doc it wasn't working. i was on 45mg at the time (i'm a 21 year old, 250lb male). we immediately jumped to the parnate rather than increasing the nardil, with no luck. granted almost all my trials over the past three 1/2 years have been cut short because I expected an immediate response like on the nardil, and couldn't face the idea of waiting to feel better. now I'm on selegiline (eldypryl) and plan on giving it and all future trials six weeks no matter how shitty they make me feel at first. in the last three years, I've had a few creative breakthroughs, but no AD effect. i tried the nardil again, this time at 90 mg and after two weeks, my parents visited, and i couldn't look them in the eyes- i was totally withdrawn, a zombie. i wanted to try it for six weeks, even though it seemed to be having a paradoxical reaction, but i think it really scared my parents, and so now i'm on seleligine. my pdoc is top notch, very liberal, willing to try anything aggressively, which is how i like it since side effects mean nothing to me when weighed up against the possibility of a therapeutic effect. you could chop off my balls if i was promised a lifetime of feeling like I did on the nardil. please explain what you mean by "initial effects without a true anti-depressant effect" as this seems to fit my case perfectly. my doc says the nardil just simply pooped out (tachyphylaxis) and although it gave me initial remission, is not the med for me. problem is, I haven't felt ANYTHING from any med or 15 ect treatments since. recently i developed the theory that since i was depressed for so long, my body reacted to a foreign chemical almost immediately, but as soon as it became used to it, the drug no longer worked. i take this theory partially from my experiences smoking pot. if i don't smoke for a while, I'll get real creative/more social/lose some anxiety that first time i puff. but if i try it again the next day, i'll feel next to nothing. Please provide me with any insight you may have, as knowing what it feels like to not be depressed has made these past three years a living hell. i almost wish i never experienced the nardil feeling, so I wouldn't know what I was missing. however, there has to be some explanation. do you think if I stayed on the nardil this second time for six weeks, the withdrawal/nervousness/brain deadness would go away? why did it seem to work and now give me paradoxical reactions? (on 90mg, twice the dose i was on when it worked and bummed out). after the selegiline, i plan on trying parnate again, but this time for six weeks. having teirs everything, i now feel that i didn't give any of the meds enough time to kick in, and since I (seemed to) respond to the nardil, this could bode well for an extended parnate trial. sorry for the length- I would greatly appreciate your opinion, as the mystery had plagued me for years, expecially since I had everything I wanted in my grasp and have tried everything to get it back unsucessfully.
poster:matt66
thread:205524
URL: http://www.dr-bob.org/babble/20030306/msgs/206563.html