Posted by SLS on February 23, 2003, at 11:38:03
In reply to Re: New Thoughts » Peter, posted by Ritch on February 23, 2003, at 9:39:37
There is no reason why an MAOI cannot be combined with any psychostimulant as long as prudence is exercised. It is probably a good idea to check for hypertension when first adding a stimulant to Parnate, especially after the first dose. Parnate is known to infrequently produce hypertensive episodes, even when used as monotherapy and in the absence of tyramine. Personally, I have tried Parnate 120mg + desipramine 300mg + (Ritalin or Dexedrine). It is my impression that Parnate is used most often in this type of combination. My guess is that the type of depression most often chosen to treat using this combination strategy is either anergic or bipolar. Parnate has traditionally been the MAOI of choice in these cases. However, it is likely that any irreversible MAOI would have the potential to be successful.
methylphenidate (Ritalin, Concerta, Metadate)
amphetamine salts (Adderall)
Documentation can be found within Dr. Bob's Tips: