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Re: Straterra

Posted by paulk on February 10, 2003, at 17:00:20

In reply to Straterra irritablity, posted by Peter S. on February 10, 2003, at 11:34:29

> I started on Straterra at 10mg for 2 days and went up to 20mg. I've noticed an increase in irritability (also apparent at 10mg) which is extremely unpleasant- although I have had more energy. My mood has been pretty bad and I think worse than before. I really want to stop, but I want to make sure that I'm giving it a fair trial. I'm also taking Lamictal and Neurontin.
>
> I wish there was more data on whether the irritablity goes away in time. I really have difficulty tolerating it. Sounds like some other people are having same effect. Has anyone noticed it going away?
>
> Any psychopharmacologists know why Straterra might cause irritability? Does norepinephrine cause irritability? I was thinking that maybe if it's not balanced out with other neurotransmitters (like serotonin)it might do this. What about combining it with an SSRI? God I hate brain chemistry!
>
Why not go back to 10mg/day - at least until the iritability goes away?
Norepinephrine can do that - you may want to take it with food to limit the peak blood level a bit - smooth things out. I take it you read how for 10% of the population it is 5 times more powerful.

This is my first day at 20mg - Seems to be pretty good.


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