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Re: Enada NADH - Sublingual vs Enteric Coated Tabs » hok

Posted by Ron Hill on February 4, 2003, at 18:55:30

In reply to Re: Try Enada (NADH)! ...whoops...nevermind, posted by hok on February 4, 2003, at 15:39:10

>You mentioned you were taking 10mg of the quick-dissolve variety. So I guess my question is whether you tried both kinds and if you've seen a difference in efficacy b/t the two (dosing differences aside).
-----------------------------

Hok,

So far I have only used the sublingual formulation. I plan to switch to the enteric coated tablets in about a month or so, but for the time being I want to continue with what is currently working.

As I see it, there are advantages and disadvantages for both the sublingual (ENADAlert NADH) and the enteric coated tablets (ENADA NADH). Both forms have the same active ingredient (reduced B-nicotinamide adenine dinucleotide). The difference is in the delivery pathway.

It is important to remember that NADH is destroyed by the acids in the stomach. Therefore, the down-the-hatch ENADA NADH tablets are enteric coated to protect them from stomach acids and, thereby, allow the NADH to make it to the intestines where it can be absorbed into the bloodstream. People vary in their ability to absorb nutrients (in this case NADH) through their intestinal walls.

The delivery pathway for the sublingual ENADAlert NADH is directly to the bloodstream through the thin membrane at the bottom of the mouth under the tongue. Please note, however, that a portion of the ENADAlert NADH dose is destroyed in the stomach when the patient (unavoidably) swallows saliva containing NADH.

The sublingual administration causes blood levels of NADH to escalate quickly then drop off. By contrast, the down-the-hatch administration has a slower, more gradual elevation of blood levels.

ENADAlert NADH is marketed as a product to alleviate jet lag and to minimize the effects of sleep deprivation. I’ve read that the sublingual product should not be used on an on-going basis as a substitute for the down-the-hatch ENADA NADH. They did not say why.

-- Ron


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