Posted by not exactly on January 26, 2003, at 0:15:32
In reply to Re: hypersensitivity, depression » not exactly, posted by disney4 on January 24, 2003, at 14:54:28
> I tried Wellbutrin Sr twice before, and couldn't tolerate the shakiness and anxiety. I took it for about a week, and I was still shaky. Do you know if this effect always wear off? I might try it again.
The official "prescribing information" document [http://us.gsk.com/products/assets/us_wellbutrinSR.pdf] mentions that temporary stimulant side effects are common. Of particular note is the following statement under "Dosage and Administration":
"Gradual escalation in dosage is also important if agitation, motor restlessness, and insomnia, often seen during the initial days of treatment, are to be minimized. If necessary, these effects may be managed by temporary reduction of dose or the short-term administration of an intermediate to long-acting sedative hypnotic. A sedative hypnotic usually is not required beyond the first week of treatment. Insomnia may also be minimized by avoiding bedtime doses. If distressing, untoward effects supervene, dose escalation should be stopped."
Your symptoms of "shakiness and anxiety" sound like extreme cases of this. Did you notice _any_ reduction of these side effects after a week of dosing? It's possible that you didn't wait long enough, but having such severe and unpleasant symptoms persist for this long a period may mean it's not the right drug for you.
If you decide to give it one more try, I'd recommend starting at a lower dose. Use the 100 mg size (I assume you tried the standard 150's) and don't take more than 1 per day until the side effects subside. Something like Klonopin might help you through the adjustment period (I think using a "sedative hypnotic" is overkill unless you have serious insomnia). You should discuss your concerns with your doctor first.
- Bob
poster:not exactly
thread:133458
URL: http://www.dr-bob.org/babble/20030125/msgs/137571.html