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Re: Why is Klonopin? - many uses long half life » chad_3

Posted by bluedog on December 24, 2002, at 19:26:31

In reply to Re: Why is Klonopin? - many uses long half life, posted by chad_3 on December 22, 2002, at 20:31:54

> My opinion is that:
> 1) Long half life unlike xanax and ativan
> 2) Less sedating than most benzodiazepines
> 3) Long shot best benzo for Social Phobia
> 4) Good for panic at low dose
>
> 5) Good for many "antipsychotic wounded" people - the best common drug for most tardive movement disorders... Many here use it as a/p substitute once their aquired brain lesions from the a/p.
>
> 6) Combines well with the serotonergics which dominate the patented drugs right now - provided the sertonin add-in does not cause too much sedations and sexual side effects.
>
> Chad
> http://www.socialfear.com/
>
>
> > Does anybody know why almost everyone on this board who takes a benzo takes Klonopin? It definitely *is* the benzo du Jour. Once in a while I see Xanax mentioned on this board, but Valium, Ativan, Librium are almost unmentioned. Anyway, maybe they are mentioned, and I just don't see it. However, I've got to say that it seems 90% of all benzo posts are about Klonopin. Why is it the popular one?
> >
> > MB


Hi Chad, I have a question for you.

I am a long term social anxiety sufferer. I live in Australia and for whatever reasons (the reasons are always medico-political) there are many more legal restrictions on doctors prescribing Klonopin rather than Valium and the doctors actually prefer to prescribe Diazepam over Klonopin in Australia which appers to be the exact opposite of the situation in the USA.

So I guess you could say the in Australia (at least the State in which I live) Diazepam is actually the Benzo "Du Jour" with Temazepam probably sitting on an equal footing with Diazepam though Temazepam is more often used for insomnia problems. For these reasons my PDoc preferred to put me on Valium rather than Klonopin for my social anxiety.

It just so happens that Clonazepam has been the drug that has been the most heavily researched in relation to social anxiety. However have you seen the following 2001 study? I have higlighted with capitals the part of this abstract that caught my attention!!!
==================================================================================================

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11206035&dopt=Abstract

1: J Clin Psychiatry 2001;62 Suppl 1:50-3 Related Articles, Links

Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).

Jefferson JW.

Madison Institute of Medicine, Inc., and the University of Wisconsin Medical School, USA. JeffJ@healthtechsys.com

Both benzodiazepines and conventional anticonvulsants have been evaluated as treatments for social phobia (social anxiety disorder). Among the benzodiazepines, clonazepam is the best studied, ALTHOUGH THERE IS REASON TO EXPECT THAT ALL BENZODIAZEPINE ANXIOLYTICS WOULD BE EFFECTIVE FOR THIS CONDITION. Among the anticonvulsants, gabapentin and pregabalin, an analogue of gamma-aminobutyric acid (GABA), have been shown to be more effective than placebo in double-blind studies. Other than a small negative open study of valproic acid for social phobia, there is a paucity of information on whether other anticonvulsants might be useful for this condition.

PMID: 11206035 [PubMed - indexed for MEDLINE]
==================================================================================================

Chad my question for you is as follows:-

With Diazepam also being a long acting benzo can you see any reason why the reasons you state in your post about Klonopin would not also apply to Valium?

Thankyou and regards
bluedog



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poster:bluedog thread:132156
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