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Re: Wanted: OPINIONS/EXPERIENCES w/ BUSPAR, please! » ZeeZee

Posted by scoper on December 22, 2002, at 19:25:49

In reply to Re: Wanted: OPINIONS/EXPERIENCES w/ BUSPAR, please! » scoper, posted by ZeeZee on December 21, 2002, at 20:31:42

> I have been waiting until the holiday is over and my family is back home to try what my doc has recommended for now - to add Buspar to my St. John's Wort. Have you had any negative side effects from it? I took it just once and awoke around 3:00 a.m. with a wave of anxiety, which is not typical of me. That is how I tend to feel on SSRI's although 1,000 times worse. Although I'm anxious to try it in hopes of finding relief I am fearful of the effects. Any further details of your experience you could provide would be helpful.
> Thanks


The wave of anxiety you mention with Buspar is initially normal with Buspar. It even says that in the side effect profile. It has some elevation properties for the Dopamine D2 receptor, which is responsible for some excitement and nervousness out of the gate. It elevates the S1 Serotonin receptor as well, so that too will cause some nervousness. It can lower that receptor too, but only if it is aggravated. In other words, depending on your brain chemistry, it will either cause you to feel calm, or make you feel excited. All in all though, within a month, you will reach a point where you feel calmer and calmer by the day. It will last a little longer each day. You have to give yourself time to adjust to the medication, and let it work. Be patient. I reccommend a 15-30mg. dosage a day. The higher you go, the more Dopamine you will release, so be aware that at 60mg., a high dose, you will feel more antidepressant effects than antianxiety.

As to your combining it with St. John's Wort, I think it is a great idea! St. John's Wort will also cause anxiety at higher doses, and can dramatically raise Serotonin levels. So, having something there to bring down the elevated Serotonin would be good. You are lucky to have a Psychiatrist that believes in St. John's Wort, as it is effective in a milder way than the SSRI's. Furthermore, it is proven to boost Norepinephrine and Dopamine along with Serotonin, giving it a more broad usage profile than the SSRI's. St. John's is good for ADD, in my experience, and better for GAD than the SSRI's. Personally, I like the herb, and don't forget that in Europe, it is prescribed about twice as often as the SSRI's. I think it has a bad rap in this country due to the money made from the drug industry! Think about it!?

Lastly, St. John's Wort can be taken up to 1800mg.! That would be to treat OCD problems. So, it is very safe, and better tolerated than the SSRI's or Tricyclics. I advise you to try to stay on that, and consider adding some GABA or L-Taurine at night for further antianxiety effects.

Scoper.


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