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Re: Can Klonopin decrease AD efficacy? » MB

Posted by BrittPark on December 14, 2002, at 2:05:01

In reply to Can Klonopin decrease AD efficacy?, posted by MB on December 12, 2002, at 15:57:56

> I've been on Wellbutrin (again) along with Klonopin to take the *edge* (rage, anxiety, panic, neck cramps, blurry vision) off of the Wellbutrin. Anyway, the depression isn't any better. Could it be that the Klonopin is keeping the Wellbutrin from working? I've heard that benzos can make depression worse (except for Xanax...why *is* that by the way, why is Xanax different?).
>

There is certainly a lot of anecdotal evidence that klonopin can be mildly depressogenic. There are also many people who take it who continue to respond well to their ADs.

I don't think anybody knows why xanax is a mild antidepressant. There have been a few studies that showed this. Chemically xanax has one property, along with, triazolam, in that it is tetracyclic instead of tricyclic like all the other benzos.

You might try switching to xanax to test the hypothesis that klonopin is somehow blocking your response to wellbutrin. Xanax requires more frequent dosing but otherwise swaps about 1mg for 1mg with klonopin. At least that's what my psychiatrist and I have found.

Feel better,

Britt


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poster:BrittPark thread:131530
URL: http://www.dr-bob.org/babble/20021210/msgs/131766.html