Posted by Larry Hoover on December 7, 2002, at 13:29:06
This subject comes up repeatedly, but it's one of the hardest to grasp, and most doctors don't have a clue. The link below has some excellent tables, and also some really good descriptions of the sort of thing that can go on, vis a vis interactions.
Some terminology that's essential:
substrate: any substance consumed by an enzyme. The enzyme reduces the concentration, and changes the substance to something else. A substance which is metabolized by an enzyme is a substrate for that enzyme. They mean the same thing. Two different tables use these equivalent terms.
inhibitor: any substance which slows down the action of an enzyme. The net effect is the same as taking too much of any drug which is a substrate for that enzyme.
inducer: any substance which speeds up the activity of an enzyme. The net effect is the same as taking too little of any drug which is a substrate for that enzyme.
http://www.erowid.org/psychoactives/pharmacology/pharmacology_enzymes1.shtml
poster:Larry Hoover
thread:130925
URL: http://www.dr-bob.org/babble/20021203/msgs/130925.html