Posted by pharmrep on November 25, 2002, at 2:00:19
In reply to Side-effects - best data » pharmrep, posted by dr. dave on November 24, 2002, at 4:38:06
> Dear Pharmrep,
>
> Good to see you back! The idea that Lexapro has fewer side-effects than Celexa seems to be floating around again. I presented the most recent and accurate data on this a while back and invited your comments. I may have missed them so forgive me if I am needlessly repeating myself, but it would be good to be clear about your views on this.
>
> > The relative side-effects of Lexapro and Celexa are as follows
> >
> >
> > Side effect..........................Lexapro..............Celexa
> >
> > Headache............................15.8%..............19.9%
> > Nausea................................15.0%..............17.2%
> > Ejaculation disorder..............9.3%(of men)...8.8%
> > Insomnia..............................9.2%................8.6%
> > Diarrhoea.............................8.0%...............10.8%
> > Somnolence.........................6.9%................4.7%
> > Mouth dry............................6.2%...............8.1%
> > Upper resp tract infection.....6.2%...............3.9%
> > Dizziness..............................6.0%...............5.6%
> > Flu-like symptoms................5.0%...............6.1%
> > Rhinitis.................................4.9%...............5.6%
> > Sinusitis................................4.3%...............5.1%
> >
> >
> > 'Overall, the type and frequency of TEAEs (treatment-emergent adverse events) reported with escitalopram and citalopram were very similar, and are in line with AEs reported for citalopram previously. For the TEAEs listed (above) there were no statistically significant differences for incidences of these events between the escitalopram and citalopram treatment groups.'
> >
> >
> > This is the official information from Lundbeck about relative side-effects. I wonder if you still stand by the comments that Lexapro has fewer side-effects than Celexa, and that Celexa causes somnolence while Lexapro does not?
> >
> >
>***** I'm not sure i agree with all those %'s...i need to get my package inserts for both and will post (ie...Celexa nausea was 21%, not 17, and I know somnolence for celexa was 18%, not 4...but I will post what the U.S. P.I's state)...as for Lundbeck...the European studies and #'s are done separately from the U.S....I dont think they should be much different, it depends on the parameters of the study.
poster:pharmrep
thread:109458
URL: http://www.dr-bob.org/babble/20021122/msgs/129159.html