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Re: Experiences with beginning Parnate--extreme fa

Posted by fierc on November 14, 2002, at 3:02:51

In reply to Experiences with beginning Parnate--extreme fatigu, posted by e's wife on November 13, 2002, at 15:32:11

> My husband has major depressive disorder that is recurrent and treatment resistant. Over the last 20 years, he's tried many combinations of tricyclics and SSRI's which eventually fail. He's just started Parnate (as of yesterday up to 40mg/day) and is also taking Lithium which he has taken for many years. Since beginning the Parnate 10 days ago, he's been feeling very, very tired. He does not feel depressed as of day 6 or so, but still feels the tiredness. During the wash out period leading up to the Parnate, he took Zyprexa and Lithium (+ Valium for anxiety as needed). Just cut out the Zyprexa yesterday (which might be contributing to the fatigue). Just wondering if anyone else experienced the tiredness when beginning Parnate and if we can reasonably expect it to go away. Thanks!

Parnate was aweful the first 2 weeks i was on it. I got about 2-4 hrs of sleep the first 10 days and was up dazed and sedated rest of the day. Fortunately it finally passed. I now take a different MAOI Moclombimide and have experienced no side effects which struck me as weird cause I never do good with meds. Hopefully he can stick with it and it will pass in a few more days.


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