Posted by jflange on November 12, 2002, at 17:22:22
In reply to Re: WHY the weight gain w/ SSRI's???, posted by Mats on November 12, 2002, at 1:31:29
Among the various reasons for SSRI weight-gain one sees mentioned and debated are a slowing of the metabolism and carbohydrate cravings. For those of us who have gained weight on meds without a change in diet/exercise routine, these explanations seem a bit paltry. The most convincing explanation I have found is that since serotonin plays a role in the metabolization of blood glucose, manipulating available serotonin in the body has an effect on insulin and the body's fat storage. The short answer is that nobody knows definitively!
However, the side-effect does not necessarily fluctuate by dose. Even those on low doses of SSRIs have experienced weight gain. But the good news is that you are unlikely to have more weight gain if you increase the dose on the same drug.
Would love to hear what others have found in their research on this topic!
jflange
poster:jflange
thread:127321
URL: http://www.dr-bob.org/babble/20021108/msgs/127419.html