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Re: Provigil partial synergy with Klonopin

Posted by Rocket Jackson on November 2, 2002, at 21:33:07

In reply to Provigil partial synergy with Klonopin, posted by chad_3 on November 2, 2002, at 18:31:18

> Rocket -
>
> I noticed some sort of interaction between provigil and klonopin also. Provigil seems to act kind of like a serotonin 3 agonist, and partial da agonist.
>
> The PDR does state Provigil antagonizes Clozapine. I noticed that provigil - like wellbutrin and dhea - also reduced the effectiveness of Propecia I was taking. This was couple years ago - i do not care for dhea but think that wellbutrin and provigil would more likely have potential utility in polypharmacy - all just IMO since you bring up 2 useful meds I think for SP - especially the radically awesome Klonopin.
>
> Later dude - keep up the good work Doc - you add something new to the crew here!
>
> Chad
> http://www.socialfear.com/
>
>
>

Hi Chad,

Thanks for the info. I'm always fascinated with this kind of stuff, particularly from experienced and knowledgeable posters such as yourself. Considering Wellbutrin's mechanism of action, I was hoping it, along with Klonopin, would prove to be an effective combo. But it sure did nothing for me personally. In fact, I found myself much more irritable and anxious, the latter which certainly didn't benefit the SP all that much. :) And I even felt as if the WB was antagonizing the Klonopin to some extent, as I wasn't experiencing near the benefit as I was with K alone. Perhaps this combo might work for others.

And by the way, your website is great! It's nice to see an informative site out there on this frustrating condition. You, too, keep up the great work!

Rocket

P.S. I know I've read this in previous posts, but what do you find is working best for you at this point?


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poster:Rocket Jackson thread:126124
URL: http://www.dr-bob.org/babble/20021101/msgs/126231.html