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Re: trimipramine versus other TCAs » Julia

Posted by Chloe on October 22, 2002, at 21:40:08

In reply to trimipramine versus other TCAs, posted by Julia on October 20, 2002, at 10:43:18

> I am on 110mg trimipramine, but do find day time over sedation a big problem,especially as I have ME.I feel spaced out a lot of the time And it helps insomnia and agitation,but does nothing for the despair. Would changing to another, somewhatless sedating tricyclic be a good option(eg dothiepin, doxepin )or adding in some nortriptyline.I have tried increasing the trimipramine,but can't get it any higher and 110 might not be enough, but I might be able to tolerate a high enough dose of another TCA? when swopping TCAs should it be done gradually or straight swap?? I seem intolerant to most other a/ds .


Hi Julie,
I am not really much help because I find that most AD's either make me high, irritable or they don't work. But I am having good success with Doxepin, and that was one that you are considering.
It is rather sedating, but quite good for sleep and anxiety. And if I don't go over 60 mgs, I manage to stay out of the manic range. IMHO, if you are not happy with the AD you are taking, find one that fits your needs better. There are plenty of TCA's to choose from. You might not want to try Dox. if you are having problem with daytime sedation. I hear Nortripyline is a relatively well tolerated one.
Best of luck
Chloe


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