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downregulation??

Posted by turalizz on July 23, 2002, at 10:18:30

Is it a fact that increasing intercellular concentrations of a neurotransmitter results in downregulation of its receptors, or is it just a speculation on how the AD's loose their effectiveness in time?

Can someone refer me to studies about AD (especially MAOI'S) induced downregulation, how to reverse it etc.?

...and a second question: What does "receptor sensitivity" mean?


thanks,
cem


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poster:turalizz thread:113408
URL: http://www.dr-bob.org/babble/20020718/msgs/113408.html