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Re:Doxepin - Usual Dose for Sleep or Pain » Chloe

Posted by fachad on June 14, 2002, at 23:10:00

In reply to Re:Doxepin » fachad, posted by Chloe on June 14, 2002, at 20:54:45

I think the usual TCA dose for sleep or pain is 25mg or 50mg.

Some people may get by with only 10mg but others may need the full AD dose of 150 - 300mg.

I think a dr. would usually titrate the dose up until you are sleeping fine and the pain is gone, or the side effects become intolerable, whichever comes first.

Regarding the sedation at 150mg, my wife slept around the clock at first, but over a few months she got back to normal. Almost 10 years later, it still knocks her out at night, and she sleeps really hard, but by the next morning she is fine.

I hope the dox works for you.


> Fachad,
> I have to say, you really have done your research! I have a whole new respect for TCA's and your ability to understand and relay the information.
>
> I really don't want to jinx anything, because it was only one night. But the doxepin worked great! I was anxious that I would not fall asleep like with Trimip. But I fell into the black hole of sleep. God, that experience is priceless. In hind sight, I think I had a paradoxical reaction to trimip. It really caused a great deal of anxiety and angst, as well as profound insomnia and restlessness. Not to mention all the ACh rebound peeing, etc.
>
> I did wake up very refreshed this morning and in a very pleasant mood. This is highly uncharacteristic of me on ami. I am usually nasty and short fused and fussy. I AM starting to notice some reemerging scalp pain. Perhaps related to less doxepin being available to the body at only 20 mgs? I will stay at 20 for a while and hope it gets better. But as you say, I may need to bump the dose to continue to get sleep and pain relief. (AND I didn't even think the ami was doing much for the scalp burn/pain! I guess it was..)
>
> I am only taking the TCA for sleep and pain. I also take a tiny tiny (1.5 mgs) amount of Celexa. I am BP2 so I don't require alot of AD, and of course too much can make me hypomanic. But with ami, I was always in this dysphoric angry state, just with more energy to a pick fight with a good friend or family member or anyone for that matter.
> So I hope the doxepin will ease some of the grouchy, short fuse stuff, and boost my mood a bit. I got enough mood stabilizers to support taking a bit more doxepin than I did with ami...
>
> I know this is highly individualized, but what is the usual dose for "sleep" or pain? I have only seen the AD dose recommendations...They couldn't be the same. Isn't 150 mgs of Dox pretty sedating? Or does one acclimate quickly?
>
> Thanks for the link about elavil and your wife. I am so glad she found a med that has helped her control her disease, despite the miserable side effects. She must be a brave person.
>
> Thanks Fachad for sharing
> Chloe


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