Posted by JohnX2 on June 7, 2002, at 6:55:10
In reply to info- Fluid restrictions w/ Dex/Adderall extensive, posted by 3 Beer Effect on June 7, 2002, at 1:14:24
This baking soda trick will throw off your body's
balance of important electrolytes like Sodium and
Potassium. Seems most of the AEDs work on these electrolytes
on the brain one way or another..I would be concerned about using the baking soda trick if
you are taking any medicine besides dex/adderall. Even then...why
not just get the dosage adjusted?What do you think?
John
> The main way the effectiveness of amphetamines are increased is to DECREASE their urinary EXCRETION. When your urine is acidic, amphetamines are eliminated at a much faster rate than if your urine is basic. If your urine is alkaline, the amphetamines (much of which are excreted unchanged) are actually reabsorbed into your bloodstream (through the renal tubules or something like that), so with alkaline or even neutral urine your dex/adderall lasts alot longer.
> In most people, urine is usually acidic most of the time. The acid/basic balance of the blood is very tightly controlled & can't really be altered to a significant degree by food/drink.
>
> As far as the stomach goes, the information on whether the normally acidic stomach degrades or has no effect on amphetamines is scarce. Most of the amphetamine is absorbed in the intestine which has an alkaline ph (7.4 or something close to that).
>
> Food in the stomach supposedly doesn't affect the extent of absorption (unlike Ritalin) but food will greatly slow the time (tmax) to peak blood level (cmax). It is this rapidity of the rise in blood level that is responsible for much of the euphoric action of the drug- I notice the greatest efficacy & subjective effects of Dextrostat are when I take it on an empty stomach with ice-water or fat free milk.
>
> The most significant information i've found on this subject is that Baking Soda (Sodium Bicarbonate) BOTH increases the absorption of amphetamines & by alkanalizing the urine greatly decreases their excretion. There are instructions (be sure to follow/read them exactly) on the side of the box of Arm & Hammer Baking Soda on how to use it as an antacid. I used to take that on an empty stomach a half an hour or so before I took Dextrostat with plain water. It definitely works, but most medical books say that using baking soda as an antacid or urinary alkanalizing agent is BAD FOR YOUR BODY. It tends to throw off your body's acid-base balance in the long-term especially at the higher doses used to alkanalize the urine- I don't recommend this approach to anyone- I don't need to use Baking Soda anymore now that I have an adequate, proper therapeutic dose regimen of Dextrostat everyday (20 mg bid).
>
> Note- Most Antacids like Pepcid AC excetera will not work in this same way & do not alkanalize the urine to the extent Baking Soda does. Most Antacids, especially those that coat the stomach will actually will DECREASE the absorption of any drug (not sure about Tagament/Cimetadine in this case though), so taking an antacid other than Baking Soda during amphetamine therapy is the last thing you would want to do. For DiscoPuppy- I don't know if lactose intolerant people can take baking soda- I would just stick to plain ice-water if I were you.
>
> I've searched all around on trying to figure out which drinks & foods are acidic or basic & haven't found much to go on but this is what i've found:
> Avoid Cola & Coffee. These are two of the worst things to drink with amphetamines. The reason being is that not only that they are very acidic [(cola=phosphoric acid (bad)], & when caffeine occurs from or is derived from a coffee bean or kola nut it is irritating to the stomach & more stomach acid is released eventally making the urine more acidic. Even decaffeinated coffees & colas increase stomach acid secretion to a surprisingly high degree. If you must drink caffeine, take No-Doz and drink ice-water instead. Caffeine in pill form only causes the release of 1/2 as much gastric acid as an amount of coffee with an equal amount of caffeine. But Caffeine, as a diuretic/urinary stimulating agent decreases the renal reabsorption of amphetamine & probably shortens its duration of action.
>
> I don't know the ph of tea or iced tea but would like to find out since "Sweetened Southern Iced Tea" is my favorite & i'm sick of drinking plain water. Obviously, you can't put lemon in it in your tea while on amphetamines.
>
> Acidic fruit juices must be avoided- citric acid in particular. This a major problem (for me) since even Gatorade has citric acid in it (although with sports drinks, I am not sure if other ingredients are added to neutralize the ph. I guess you would have to buy litmus paper to find out. Where do you buy litmus paper anyways?- I didn't see it in the office supply section of Wal-Mart the last time I was there!
>
> I learned that Milk is alkaline, but when the fat & proteins in milk are digested, acid production is slightly increased, so it is probably best to drink fat-free milk.
>
> Unless there is some alkaline drink I don't know about (I haven't found any yet- anyone let me know if you find something- is V8 juice alkaline?), I think the best thing to do is to just drink plain ice-water, even if you don't like the taste as much as your usual morning coffee, cola, tea etc. Plain water, since it has a neutral ph of 7.0 allows hydration & normal urine flow but without potentiating the urinary excretion of amphetamines.
>
> I would like to find out the Ph of the various flavors of Gatorade, Powerade & also the Propel Fitness waters, since most people tire of drinking plain water after awhile, but I don't think they (the manufacturers) publish this info.
>
> I don't know if dehydration causes acidification of urine? Does anyone know this? But regardless, dehydration makes you tired, so it is best avoided.
>
> Ritalin doesn't have any of these drink restrictions, but you have to take it on an empty stomach, otherwise its absorption & efficacy are VERY markedly decreased, so that might be worse or better depending on the person (& how much they like Coffee).
>
> Also, avoid Ginseng at all costs! You would think the opposite, but Ginseng inhibits the actions of amphetamines.
> 3 Beers.......
poster:JohnX2
thread:108938
URL: http://www.dr-bob.org/babble/20020602/msgs/109049.html