Posted by fachad on June 4, 2002, at 19:12:19
In reply to Re: Trimipramine - (fachad), posted by johnj on June 3, 2002, at 13:59:36
I searched a medline database for hypnotics.
I was turned off by benzodiazapines after I found out that they mess up sleep architecture and prevent deep stage 4 sleep.
I had thought there was little difference between the tertiary TCAs (amitriptyline, doxepin, imipramine, trimipramine) except for degrees of H1 blockade (drowsiness) and ACH blockade (dry mouth, etc). But then I found all these articles on trimipramine and how it was unique in structure, lack of reuptake, and beneficial effects on sleep architecture.
I would expect it to have some effect on anxiety, but I don't really know.
> Hi,
>
> This has been a great thread and I was wondering how you found all that info on trimipramine? I am looking to get off nortryptline since it causes some problems when I excercise, and wonder if trimipramine might be better. I worked outside yesterday and felt like crap in the evening and woke up early so today is not very good. I need the help with sleep that is for sure.
> I think the benzo helps my anxiety, but it can possibly lead to some depression problems so I want to limit my benzo dose.
>
> One of the articles stated the following:
> <Based on experience using trimipramine, a profile of 'ideal' patient characteristics has been built up. Finally, the use of trimipramine in selected patient populations is reviewed.> Do you have any idea how I can find this information?Was the article posted just an abstract?
> You seem to know how to get your hands on some quality info and any pointers would be appreciated. Thanks, and I hope your sleep is better.
> Johnj
poster:fachad
thread:107701
URL: http://www.dr-bob.org/babble/20020602/msgs/108686.html