Posted by JohnX2 on May 5, 2002, at 18:39:00
In reply to These scary drug cocktails, posted by Automated Lady on May 5, 2002, at 9:02:10
> Just wanted to ask Americans... is it not really weird and scary to take such big combinations of drugs? In the UK it's rare to get prescribed more than one at a time (certainly not combinations like Efexor/Wellbutrin, which I've had suggested on this site). Prescribing 1 at a time doesn't work for me because i have real problems with motivation on just SSRIs, but doctors I've suggested combining to have been horrified at the idea (but the expense may have been something to do with that reaction) ;-) Do you not find you just get a huge raft of side effects?
>
> I'm also a bit worried by what I've heard about SSRIs.. that because they increase the amount of neurotransmitters in the brain the brain responds by reducing the number of receptors... taking you back to square one (in fact worse when you come off them). is this true? then what's the point?Usually an augmentation to a base medication is used to
address some side effect or issue that the base medication
does not address. Its a bit easier to test out augmentation
because you can bail on the medicine rapidly if you find
it uncomfortable (you still have your base med backing you
up).The SSRIs are effective medicines. It is believed that some
sub-types of serotonin receptors are downregulted (less
receptor density), but those particular receptors have been
linked to depression and anxiety, so down regulating them
may be useful.John
poster:JohnX2
thread:105138
URL: http://www.dr-bob.org/babble/20020503/msgs/105213.html