FACHAD: you forgot my second question, here it is: » fachad

Posted by Janelle on April 5, 2002, at 14:56:44

In reply to How Many Half-Lives Until it's Gone? » Janelle, posted by fachad on April 5, 2002, at 11:51:28

Fachad - I had asked two questions about half-lives and elimination of meds, but you seem to have missed the second one so I've copy/pasted it here for you to please answer! Thanks:
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2) Please humor me and bear with me a bit more here cuz I'm still not getting the whole story with this half-life stuff (no pun intended!) ...
Okay, taking your example of a drug concentration of 100mg/l with a 2 hour half-life, the drug would be reduced as follows(?):
1PM 100 mg/l
3PM 50 mg/l
5PM 25 mg/l
7PM 12.5 mg/l
9PM 6.25 mg/l
11PM 3.125 mg/l
1 AM 1.56 mg/l (I suppose at this point the drug could be considered out of the body)
Adding this up, I'm getting 6 half-lives, but you said that after FIVE half-lives, a drug is considered gone??
ALSO, what confuses me even more is what if the concentration was doubled, and it was 200 mg/l of the drug with a 2 hour half life -- wouldn't it take MORE half-lives to get rid of the higher concentration of the drug?
I would think that the higher the concentration of a drug, the more half-lives it would take to eliminate it???????
So, I don't understand how no matter what the concentration of a drug, it is always 5 half lives to eliminate it from the body??????? How can this be? HELP!!!!!!!!
Thanks!

Thread

Could someone explain HALF-LIFE w/ example! Janelle 4/4/02
...
RELATIONSHIP BTW 1/2 LIFE AND ONSET OF ACTION? Janelle 4/4/02
FACHAD: 2 questions 4 U (1/2 lives revisited!) Janelle 4/4/02
Relationship btw 1/2 life and onset of action? Janelle 4/5/02
SUNNELLY: could you answer this one also please?! (nm) Janelle 4/5/02
Re: Relationship btw 1/2 life and onset of action? Elizabeth 4/5/02
elimination half-life stuff Elizabeth 4/5/02
How Many Half-Lives Until it's Gone? » Janelle fachad 4/5/02
Re: Relationship btw 1/2 life and onset of action? » Janelle IsoM 4/5/02
ELIZabeth: what does ^- mean? (nm) » Elizabeth Janelle 4/5/02
How can 1/2 life be SAME for DIFF concentrations? Janelle 4/5/02
FACHAD: what does GC/MS stand for? (nm) » fachad Janelle 4/5/02
ELIZABETH: what do AFAIk and HTH stand for?! (nm) » Elizabeth Janelle 4/5/02
FACHAD: you forgot my second question, here it is: » fachad Janelle 4/5/02
What does ^- mean in a computation? Janelle 4/5/02
Re: What does ^- mean in a computation? » Janelle JohnX2 4/5/02
What ^(-5) means » Janelle IsoM 4/5/02
AFAIk/as far as I'm concerned HTH/hope that helps (nm) » Janelle IsoM 4/5/02
GC/MS = Gas Chromatography / Mass Spectrometry » Janelle fachad 4/5/02
Re: How can 1/2 life be SAME for DIFF concentrations? » Janelle IsoM 4/5/02
Re: How can 1/2 life be SAME for DIFF concentrations? » Janelle JohnX2 4/5/02
2nd Question- It's All Relative » Janelle fachad 4/5/02
See Above Post » Janelle fachad 4/5/02
Re: FACHAD: 2 questions 4 U (1/2 lives revisited!) » Janelle Sunnely 4/5/02
ISO: thx, how do you raise to a negative number: Janelle 4/5/02
ISO: you are GREAT! But shouldn't it be AFAIc for: Janelle 4/5/02
...
Re: Adam, I have no idea what you did! what is ''e''? 2sense 4/15/02

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