Posted by TSA West on March 27, 2002, at 18:53:41
In reply to Effexor Weight Gain / Help Me!, posted by Rxcuriousity on March 27, 2002, at 12:59:10
Go on Buproprion SR: "Preliminary studies suggest that Bupropion SR, approved for depression and smoking cessation, is an effective adjunct to diet for weight loss. We conducted a 6-month multi-center, randomized, double-blind, placebo-controlled, parallel-group study to test the safety and efficacy of Bupropion SR as an adjunct to a balanced energy-restricted diet and lifestyle program to treat obese adults. We enrolled 327 women and men, aged 18-65 years, with BMIs of 30-43. We excluded subjects who had a history of seizures, anorexia, bulimia, depression, psychosis, cigarette or substance abuse. After a 2-week run-in period subjects were randomly allocated to placebo, 300 mg/day, or 400 mg/day Bupropion SR. The lifestyle intervention included an energy-restricted diet (600 kcal deficit), use of 2 meal replacements/day, recording miles walked (pedometer), and a lifestyle diary. Subjects received dietetic counseling every 2-4 weeks. Retention rate at 24-weeks was ~70% and was similar in all groups. The weight loss (% of initial weight) and loss of >5% at 6 months (intention to treat analysis) are summarized in table."
--Diabetes, June 2001: "Buproprion SR Significantly Enhances Weight Loss When Used with a Moderate-Intensity Lifestyle Intervention"
poster:TSA West
thread:100577
URL: http://www.dr-bob.org/babble/20020327/msgs/100604.html