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Zoloft gave me mania, so SAM-E could also?

Posted by 3 Beer Effect on March 23, 2002, at 23:45:41

In reply to Re: Does l-phenylalnine inhibit natural dopamine prod? » 3 Beer Effect, posted by Ron Hill on March 23, 2002, at 23:11:09

I have only gotten mania from one med Zoloft 100 mg- which is the only anti-depressant that has ever worked for me but caused horrible insomnia, but the happiness, optimism, & high energy from the zoloft eventually ended up turning into pretty self-destructive behavior (drinking, cocaine etc) & culminated in a DUI & also getting knocked unconscious (& sent to the hospital) by a big redneck in a fight near the sixth street entertainment/bar district in Austin, TX.

I never have mania when not on medication, but i've heard SAM-E is prone to causing mania so bipolar people shouldn't take it. (But I am taking Lamictal 100 mg as a mood stablizer, which seems like a placebo pill but might offset any mania that SAM-E could cause). But Sam-e seems hideously expensive (even at Costco/Sam's Club)- especially since I have health insurance so most of my prescription meds only cost $15-35 a month for brand names. I'm not sure what dose you have to take for a good AD effect, i've heard anywhere from 200 to 1,600 mg. 1,600 mg would be very (hideously) expensive since even a 30 day supply of 200 mg/day probably costs more than generic prozac.

Also, it seems as though SAM-E works in people whose methyl donor system (don't know much about what SAM-E does obviously) has aged or isn't functioning properly. If you are in your early twenties doesn't that mean SAM-E is less likely to work than if you are middle aged & your methyl donor thing isn't as efficient?


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poster:3 Beer Effect thread:99751
URL: http://www.dr-bob.org/babble/20020322/msgs/99764.html