Posted by Bekka H. on March 21, 2002, at 0:45:54
In reply to Dexedrine vs. Adderall pharmacology, posted by 3 Beer Effect on March 18, 2002, at 23:11:09
Keep in mind that Vitamin A, & anything acidic like fruit juices or cola increases the excretion, reduces absorptions & lessens the effects of any amphetamine. So it is best to drink water. Anything that reduces stomach acid or that increases the alkalinity of your stomach increases the absorption of amphetamines & lessens urinary excretion thus prolonging its duration of action. Baking Soda, which is very alkaline, is the best agent for this purpose- On the side of the Arm & Hammer box is a recipe for Baking Soda antacid. If you take this with your amphetamine you will notice a huge difference.
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************************************************Hi 3 Beers, it's good to see you here again.
I don't mean to nit-pick, but you wrote Vitamin A up there. Did you, by any chance, mean Vitamin C?
I think this acid-base problem has to do with urinary acidification and urinary alkalinzation. The pH of the stomach is very low (i.e., highly acidic), so the problem isn't there; otherwise, the medicine would be destroyed immediately. I'm pretty sure that much of the amphetamine is excreted unchanged in the urine, and it the pH of the urine that either hastens (if acidic) or delays (if basic) elimination. Oops! I just re-read your post and I see that you said that. I was confused by your comment about "anything that reduces stomach acid."
And, yes, even sodas can increase the acidity. One reason many sodas, even sugar-free ones, are bad for your teeth, is that most of them (especially the colas and diet colas) contain phosphoric acid, which is supposed to do a lot of damage to the teeth. I have to check on the pH of phosphoric acid. I wonder how it compares with fruit juices as far as acidity is concerned.
By the way, this urinary acidification/urinary alkalinzation problem does not occur with Ritalin and other forms of methylphenidate because MPH is metabolized by the liver to inactive products.
Anyway, this is a problem for me because I find dexedrine very helpful, and I really like fruit juice in the morning. So much of what I eat/drink is acidic. I really have no desire to drink or eat baking soda or TUMS all day long!
poster:Bekka H.
thread:98610
URL: http://www.dr-bob.org/babble/20020318/msgs/99158.html