Posted by djmmm on March 14, 2002, at 14:02:36
In reply to Re: SLS (Scott), anti-poopout agents? CCB's, posted by johnX2 on March 13, 2002, at 19:19:50
>
> use of calcium channel blockers in
> ultra-rapid cylcling
> nuerobiology treatment resistant depression
>
> http://www.acnp.org/g4/GN401000110/Default.htm
>
>
> >
> > Have you seen this Naltrexone anti-SSRI poop-out tip in the pbabble tips section? It look kind of hoky.
> >
> > But Naltrexone is an opioid-antagonist.
> > And as you may now, these NMDA antagonists involved in synaptic plasticity mitigate opioid
> > tolerance.
> >
> > So I don't if this is some kind of a "work-backwards" ploy but it looks intriguing.
> >
> > Btw, did you know that the 5ht-2 receptor is gated to NMDA conductance?
> >
> > Also, amphetamine releases serotonin via a diffusion mechanism at serotonin receptors.
> >
> > This whole poop-out thing is tied together in
> > my shoot from the hip view.
> >
> > Maybe need more poop-out stabilizers?
> >
> > Something atypical:
> >
> > Naltrexone, Memantine,
> >
> > This other medicine Acamprosate (a GabaB med + NMDA antagonist) is fast track FDA approval for
> > alcoholism for Forest Labs and is being looked at also for treatment resistant bipolar disorder (it is available in europe).
> >
> > I also saw some good darts at calium channel
> > blockers like nimodipine.
> >
> > Still curious about this Naltrexone dude.
> > Maybe you can reach that guy by email and find out what his thinking is?
> >
> > Best wishes,
> > John"poop-out" has to be caused to *too* much serotonin...why do antagonists like buspar work?...seems like activating the 5-ht2 receptors relieves "poop-out" symptoms in many...
Take a look at the symptoms of *too much* serotonin.
5ht2 acting drugs are given for serotonin syndrome...
I wonder If *lowering* the SSRI dose (when symptoms first appear) would help?
poster:djmmm
thread:97813
URL: http://www.dr-bob.org/babble/20020313/msgs/97995.html