Posted by Jason911 on March 5, 2002, at 10:52:31
In reply to Re: Just look. Take it or leave it. SELEGLINE COMBO!!!, posted by Eloy on March 5, 2002, at 4:35:30
About the aging, it won't be proven until another 30-40 or more years because the people didn't take the selegiline for life extention until the 1980's, so only time will tell. If the studies are any indication, it should increase life-span via keeping your brain healthy and slow down it's dopaminergic decline with age. It protects these cells. Like scientists know, after the age of 50 people's dopamine counts declines by anout 13% per year!! This is why you see the typical 75 year old slow (mentally) to recognize, react, and so on. Well in theory, at the age of 80 you should be mentally capable of a person in his 50's! Death occurs normally when the dopamine cells' count is at about 30% of what it was when you were younger. Not to say you wil live forever, you can just die for other reasons (heart attack (which Omega-3 can help considerably, accident, etc.). Dopamine plays a critical role in concentration, alertness, and drive; our ability to distiguish 'experience'. Now, as for a substitution for AD's and especially those dreaded SSRI's the selegiline+phenylalanine is a wise decision before resorting to these meds as the S&P combo is less-likly to cause any side-effects. The only way one should experience side-effects is if one's problem is not dopamine related, i.e serotonin related. If you don't experience constant sadness, suicidal thoughts, sleep all the time, then the selegiline combo could work quite well for you. Like the posts recently put on this board about people on Effexor (another SSRI) and having sexual dysfunction even after quitting the meds for quite some time is just a scary thought. You won't have to worry about any of this on the combo (probably an increase in libido, sex drive). It is relatively harmless, especially when taken at low dose and does so much good for not only your mood, possibly, but your brain itself! In addition to selegline partially preventing the breakdown of dopamine (MAO-A also breaks it down a little) it's the PEA that seems to have the real mood brightening effect in people. PEA is the chemical that is released when we fall in love and walk around all day in a great mood and well.... in love! The selegiline stimulates (especially with the l-phenylalanine combo) the part of our brain that affects drive, motivation, and memory. It put that spark back into our live's that we have been lacking for so long! Knoll's deprenyl discovery occured in the 60's in Bulgaria. It was originally developed as an anti-depressant with the mindset of increasing dopamine levels through MAO-B inhibition alone as it was thought that dopamine was broken down by MAO-B only. Well that was not the case as MAO-A plays a part in this as well. But Knoll did not give up and eventually found it's reall amazing potential. The US has yet to acknowledge it's anti-depressant effect. It wasn't until the 1990's that Knoll discovered it's true clinical use for us depressed people. It's worth a try. I don't want to see you get into all of those side-effect problems with all of those other anti-dpressants and it's worth giving it a shot! You should find it quite activating and mentally stimulating and sexually stimulating. Hell, Somerset (the company that makes Eldepryl (selegiline)) recently did a trial on a Selegiline patch to treat depression, and people on this very board reported amazing benefits. The purpost of the patch was to release higher amounts of deprenyl into the bloodstream while also allowing the patient to not have to observe dietary restrictions that accompany MAOI's. The FDA will make it's approval a long and drwn out process and won't be seen in the near future. But now, right now, there is an answer. Give it a try. -Jason911
> Sounds deep, so are you saying that there's a kinda combination medicine that could work better then the common SSRI's and AD's? Without using the big chemical jargon could you please break it down into laymens terms for me to understand, i'm sorry, it's just that i'm a true blond. In short, what is the panacea combo you discovered, and how is it better, and can it really slow down a persons degenerative aging too?
poster:Jason911
thread:96388
URL: http://www.dr-bob.org/babble/20020301/msgs/96497.html