Posted by JohnX2 on February 22, 2002, at 11:54:27
I once tried Imitrex for my headaches at my
GPs office and they stuck a big ugly needle
in my arm and it turned my skin all red.
It seemed to help my headache a little for a while,
but I didn't have the symptoms of migraine that
they asked about.Serzone is definately helping alleviate my
headpain (as well as Klonopin and Topamax). Serzone
was the only AD to do so. Others made it worse
including Zoloft. When I take Serzone it also causes
my skin to flush in a manner similar to the Imitrex
shot.I'm thinking the Serzone flush is caused because
Serzone has a metabolite mCpp that is a dirty
serotonin agonist whereas Imitrex has a cleaner
metabolite that is selective for the 5ht-1b and
5ht-1d receptors. Anyways both meds are therefore
agonists at those receptors. The only other SSRI to cause
this flush for me was Paxil, but it didn't work
as an AD.Anyone else experience this flushing in the
skin and get relief from migraines or other
types of headaches?-John
poster:JohnX2
thread:95100
URL: http://www.dr-bob.org/babble/20020222/msgs/95100.html