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Provigil vs. other psychostimulants

Posted by 3 Beer Effect on February 19, 2002, at 1:33:39

In reply to Re: Modafinil vs. Adrafinil Michael D, posted by Rick on February 18, 2002, at 22:07:30

I read somewhere that if you have prior experience with the "hard" psychostimulants like Dexedrine, Adderall, Desoxyn, Ritalin, Concerta or Focalin then you will probably be dissapointed with Provigil because it is not nearly as powerful as the above drugs (although it lasts much longer).

But if you are so-called "naive" with stimulants, then Provigil 200 mg would probably be a great medication for you. It it also good because it is a once a day med so people at work won't see you taking a pill during your lunch break & think you are a

In the study I read the "naive" subjects did very well on Provigil 200 mg, while Dexedrine users who agreed to switch to Provigil often dropped out of the study & started taking Dexedrine again, were non-compliant, & in general had difficulty switching to Provigil.

As a case in point I used to be on a high dose of Ritalin (20 mg 2x per day). I also used to abuse Adderall (obtained from friends) the night before exams or before college parties to be more social. This morning I took 200 mg of Provigil on an empty stomach & could still not get out of bed, while a "naive" stimulant user probably would have been up, ready to take on the world, & be singing in the shower.
I then took another 100 mg of Provigil about 2 hours later (still with an empty stomach) & still lounged in bed. Finally, I had to resort to taking 50 mg of Primatene ephedrine hcl w/ 2 mg of Klonopin to offset the horrible ephedrine side effects, & for the rest of the day I was awake & incredibly productive.

Interestingly, I noticed that with 2 mg of Klonopin I had no social anxiety with the 50 mg ephedrine hcl (the max dose of ephedrine which is probably the most anxiety/nervousness/side effect ridden stimulant out there- if I take ephedrine by itself I am a nervous wreck
Perhaps, any psychostimulant (EXCEPT Ritalin/Focalin/Concerta which tends to make people shy/introverted & focused on their work rather than other people) combined with the right dose of Klonopin will make social phobia go away.

When I took Dexedrine 5 mg 2x per day WITH NO OTHER MEDICATIONS I had a major increase in self-confidence, self-esteem, immediate relief from major depression, & very little social anxiety & even some social disinhibition. Personally, I haven't experienced any of these social enhancing effects with Provigil, which is why I am hoping to switch back to Dexedrine in a few weeks. I am going to try the Dexedrine spansule b/c I think that because it has a subtle & long action it would work better for social phobia than regular Dexedrine, although (unfortunately) it would not work as well for ADD/psychostimulant purposes. But I have never heard of anyone who has tried the Dexedrine Spansules, so they might "suck" like Ritalin SR (a pretty worthless drug).

Anyways I am happy that I have found the right combination for me after months of SSRI/Effexor/Remeron agony-
1-- Lamictal (mood-stabilizer/anti-depressant); 2-- Non-Caffeine prescription Stimulant {Provigil or Dexedrine] (to get out of bed in the morning & to reduce timidity (from low dopamine) & cause social disinhibiton;
3-- Most importantly Klonopin (although Klonopin makes you kind of "dumb" & seems to affect short term memory).

So I guess the moral of the story is, once you have takeb "hard" ADD stimulants you have a very hard time going back to "soft" stimulants like Provigil or Adrafinil----- Kind of like how people who take the pain killers for chronic pain Dilaudiud/Numporphan/Morphine/Percocet have a really hard time when there doctor refuses to give them those meds anymore & puts them on the weaker painkillers Vicodin or Codeine.




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