Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: RE: Using Serzone to Raise Levels of Other Meds Cam W.

Posted by Rick on December 27, 2001, at 15:48:50

In reply to Re: RE: Using Serzone to Raise Levels of Other Meds Rick, posted by Cam W. on December 26, 2001, at 19:04:43

Cam -

Thanks, that definitely helps clarify things.

But let me distill this to my primary question, to see if you have a feel for it or at least can make an educated guess (I'm certainly not looking for a "blanket statement"):

Assuming the patient has a "typical" cytochrome system with respect to the relevant enzymes, is it reasonable to think that a very small dose of Serzone, e.g. 75 mg, might lead to a significant metabolic inhibition? Or does this seem unlikely? All of the Serzone interaction studies I've seen are based on a typical monotherapy dosage of 400 mg, which says nothing about what the interaction effects (if any) from a lower dosage would be.

Thanks,
Rick


> Rick - I think that the pdocs I know use it to primarily raise levels of other drugs (without having to take higher doses of those drugs), while at the same time hoping for a little extra antidepressant activity.
>
> As for how to do it; I believe that is very individualized. Many factors have to be taken into consideration (past med use and response, what is hoped to be accomplished with the augmentation, disorder - and/or subtype - being treated, supposed status of one's cytochrome system, etc., etc., etc.).
>
> I do not think that I could make a blanket statement for using this type of therapy, nor do I think that it is an option for everyone. I do find that this sort of augmentation is fairly much a "last gasp" strategy, when most others have failed.
>
> I tend to think that this sort of therapy is from the "let-us-throw-a-bunch-of-treatments-against-the-wall-and-see-which-one-sticks" school of treatment. I am not a big fan of this, but sometimes one has to resort to whatever works.
>
> - Cam


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Rick thread:87093
URL: http://www.dr-bob.org/babble/20011222/msgs/87973.html