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Am I the only one who's tried topamax + lamictal?

Posted by JohnX2 on December 22, 2001, at 20:44:29


The topamax is the 1st anti-convulant with
no blurry vision,stupor,crummy speech,etc.
Just benzo side effects like slight sedation and
relaxation and less headaches.

It works on GabaA neurons kinda like Klonopin,Diazepam,
et,al and also on the glutamate nueuron AMPA.

I would expect the GabaA action to give benzo side
effects and the AMPA to give the other typical
anti-convulsant side effects.

The AMPA receptors from what I understand are usually
tightly couply to the NMDA receptors which lamictal
modulates. So I'm wondering if when you add Topamax
onto lamictal if this impacts the side effects of
Topamax's action on AMPA?

-John


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poster:JohnX2 thread:87721
URL: http://www.dr-bob.org/babble/20011222/msgs/87721.html